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Dr. Yadagiri Kommagalla

  • Office

Research interests

 – Polymer re-cyclization of soft (PUR) and rigid (PUR) foams

– Process development for the starting material re-production from PUR foam

– Mechanistic studies of catalyzed depolymerization reactions


Curriculum vitae and education

May 2022- present

Postdoctoral Fellow at CAT Catalytic Center, ITMC, RWTH-Aachen, Germany

May 2019- April 2022

Post-doctoral Researcher at ITMC, RWTH Aachen University, Aachen, Germany.

The main research activity: Design & Development of catalytic methods

For the reduction of Amide, Amino acid and Peptides & Proteins

Supervision of bachelor- and master theses

Oct 2015 – March 2019

Specially Appointed Researcher- Osaka University (Prof Naoto Chatani)

The main research activity: Design and Development of methods for C-C and C-X bond formation using transition metal catalysis

Supervision of bachelor- and master theses

Nov 2014 – Oct 2015

Research Associate- Gifu University-Prof Hiromune Ando

Development and structural optimization of new series of sialosides as

CD22- specific inhibitors

Jan 2008 – July 2014

Ph.D. Student at CSIR-National Chemical Laboratory, Pune, India

(Savitribai Phule Pune University)

Area: Organic Synthesis, Medicinal Chemistry and Catalysis

July 2005- May 2007

M.Sc Chemical Sciences at Pondicherry University, Puducherry, India

Selected publications

  1. “Rh(III)-Catalyzed Reaction of α-Carbonyl Sulfoxonium Ylides and Alkenes: Synthesis of Indanones via [4+1] Cycloaddition” Yadagiri Kommagalla, Shunsuke Ando and Naoto Chatani (Org. Lett., 2020, 22, 1375–1379)
  2. “Cobalt-Catalyzed C−H Iodination of Aromatic Amides with Molecular Iodine through the Use of a 2‑Aminophenyloxazoline-Based Bidentate-Chelation System” Yadagiri Kommagalla and Naoto Chatani (Org. Lett., 2019, 21, 5971−5976)
  3. “A Computational Study of Cobalt-Catalyzed C-H Iodination Reactions Using a Bidentate Directing Group with Molecular Iodine” Ken Yamazaki, Yadagiri Kommagalla, Yasuke Ano, Naoto Chatani (Org.Chem.Front., 2019, 6, 537–543)
  4. “Cobalt-Catalyzed Chelation Assisted C–H Iodination of Aromatic Amides” Yadagiri Kommagalla, Ken Yamazaki, Takuma Yamaguchi, Naoto Chatani (Chem. Commun., 2018, 54, 1359–1362)
  5. “Cobalt(II)-catalyzed C-H functionalization using an N,N’-bidentate directing group” YadagiriKommagalla, Naoto Chatani (Coord. Chem. Rev.,2017, 350, 117–135)
  6. “Electronic Control on Linear versus Branched Alkylation of 2-/3-Aroylbenzofurans with Acrylates: Combined DFT and Synthetic Studies” Kolluru Srinivas, Yuvraj Dangat, Yadagiri Kommagalla, Kumar Vanka, and Chepuri V. Ramana (Chem. Eur. J. 2017, 23, 7570–7581).
  7. “Cobalt-catalyzed chelation assisted C–H allylation of aromatic amides with unactivated olefins” Takuma Yamaguchi, Yadagiri Kommagalla, Yoshinori Aihara and Naoto Chatani ( Equal Contribution)( Chem. Commun., 2016, 52, 10129–10132)
  8. “Re-engineering of PIP3-antagonist triazole PITENIN’s chemical scaffold: development of novel antifungal leads” Sravani Pulya, Yadagiri Kommagalla, Duhita G. Sant, Shweta U. Jorwekar, Santosh G. Tupe, Mukund V. Deshpande and Chepuri V. Ramana (RSC Adv., 2016, 6, 11691–11701).
  9. “The NEU1-selective sialidase inhibitor, C9-butyl-amide-DANA, blocks sialidase activity and NEU1-mediated bioactivities in human lung in vitro and murine lung in vivo” Sang W Hyun, Anguo Liu, Zhenguo Liu, Alan S Cross, Avelino C Verceles, Sadagopan Magesh, Yadagiri Kommagalla, Chandrababunaidu Kona, Hiromune Ando, Irina G Luzina, Sergei P Atamas, Kurt H Piepenbrink, Eric J Sundberg, Wei Guang, Hideharu Ishida, Erik P Lillehoj, and Simeon E Goldblum. (Glycobiology, 2016, 26, 834).
  10. “Ruthenium(II)-catalyzed switchable C3-alkylation versus alkenylation with acrylates of 2-pyridylbenzofurans via C–H bond activation” Yadagiri Kommagalla, Venkanna Babu Mullapudi, Fredi Francis and Chepuri V. Ramana (Catal. Sci. Technol., 2015, 5, 114–117).
  11. “Ru-Catalyzed Branched versus Linear Selective C3-Alkylation of 2-Aroylbenzofurans with Acrylates via C-H Activation” Yadagiri Kommagalla, Kolluru Srinivas and C. V. Ramana,  (Chemistry A European Journal, 2014, 20, 7884–7889).
  12. “Optimization of the anti-cancer activity of phosphatidylinositol-3 kinase pathway inhibitor PITENIN-1: switching a thiourea with 1,2,3-triazole” Yadagiri Kommagalla, Cornea, S., Riehle, R.,  Torchilin, V., Degterev, A., C. V. Ramana, ( MedChemComm, 2014, 5, 1359-1363).
  13. “Target cum flexibility: simple access to benzofuran conjugated sugar and nucleoside derivatives” Yadagiri Kommagalla, Kolluru Srinivas and C. V. Ramana (Tetrahedron Lett, 2013, 64, 1824-1827)
  14. “The influence of electronic factors on Pd-mediated cycloisomerization: a systematic investigation of competitive 6-exo-dig versus 7-endo-dig cyclizations of sugar alkynols” I. Boddeti, B. Srinivas, Yadagiri Kommagalla, M. N. Deshmukh, R. G. Gonnade and C. V. Ramana (Tetrahedron, 2009, 65, 9819-9832)


  1. “Small Molecule Inhibitors of PI3-Kinase Signaling” Alexei Degterev, Chepuri V. Ramana, Jinbo Lee, Yadagiri Kommagalla., (Patent No: PCT/US2014/031016, US9701646, US20160297777, WO2014153337 A2).
  2. “A process for the preparation of anti-inflammatory aroylbenzofuran compounds” C. V. Ramana, Yadagiri Kommagalla, Kolluru. Srinivas, (Patent No: WO2015029062 A1, PCT/IN2014/000546, US20160229827).
  3. “New 1,2,3 triazole derivatives as anti-fungal drugs” C. V. Ramana, M. V. Deshpande, Yadagiri Kommagalla, Santosh G. Tupe, (Patent No: US9981923B2).

Awards + Scholarships

Dec 2007

CSIR- National Eligibility for Lecturership and Junior Research Fellowship